The need for evidence generation for medical decision making has become paramount in recent years, driven in part by technology innovation, a faster regulatory approval process, and rapid changes to the healthcare landscape in the US.
Traditional methods of generating evidence, from single data sources and perspectives, often no longer meet the needs of our complex health system. HealthCore has the data assets and expertise necessary for going broad and deep in real-world evidence generation.
We have seen growing interest in collaborations between life sciences, large payors, and key opinion leaders in clinical practice [1,2]. Such collaborations ensure that the research questions, study design, and study end points are relevant and meaningful to all stakeholders. The end results are effective dissemination and direct utility in decision making. In addition to many common therapeutic areas, we have also expanded our research to rare diseases and infant populations [3,4].
Given the fragmentation of health data and the growing complexity of research questions, a single data source is unlikely to be able to provide a “one size fits all” solution. Our research team has conducted multiple studies by integrating administrative claims data with medical chart review and abstraction, patient and physician surveys, laboratory results, genomic results, and patient support programs, among other data sources [5,6]. Each of these data sources provides a unique view and perspective of the healthcare ecosystem. The ability to integrate different data sources enables us to conduct research and answer complex questions effectively. Recent integrations have been carried out without any exchange of protected health information between our organization and external entities. We have been able to achieve this by using innovative matching technology. This has allowed for the connection of different health data with minimal risk of re-identification and without compromising the accuracy of the matching.
