HealthCore
Sponsor
August 2022

HealthCore is a proud sponsor of ICPE 2022. Visit us in-person at Booth #401/500, connect with our experts, and see our latest research in COVID-19 and pregnancy, among other topics. For more information, please visit https://www.eventscribe.net/2022/ICPE/.

Skills Course:

Wednesday, August 24, 2022 | 2:00 PM – 6:00 PM CEST

Using Pharmacoepidemiology Database Resources to Address Drug Safety Research

Presentation on Data Validation Approaches in Pharmacoepidemiology
Daniel Beachler, PhD, MHS, Director of Research, Safety and Epidemiology, HealthCore, Inc.

HealthCore Presentations

Wednesday, August 24 – Sunday, August 28

Click the title of each poster below to view the abstract.
*HealthCore authors are indicated in bold.
Presentation Session Title Authors Affiliations

Oral Presentations

Friday, August 26
6:15 – 6:30 pm CEST

Pharmacoepidemiologic Methods and SARS-CoV-2

[82] Adjusting for Data Observation Delay in Near Real-time Safety Surveillance of COVID-19 Vaccines Using Administrative Claims Databases

Chillarige Y1, Hu M1, Feng Y1, Shi X1, Zhou CK2, Wong HL2, Jiao Y1, Lloyd P2, Amend KL3, Beachler DC4, Secora A5, Kline AM6, Clarke TC2, Ogilvie R7, Reich C8, McMahill-Walraven CN9, Seeger JD7, Anderson SA2, Shoaibi A2

1Acumen LLC, Burlingame, CA, USA, 2Food and Drug Administration, Silver Spring, MD, USA, 3Optum, Bloomfield Hills, MI, USA, 4HealthCore, Inc., Wilmington, DE, USA, 5IQVIA Government Solutions Inc., Charlottesville, VA, USA, 6CVS Health, Woonsocket, RI, USA, 7Optum Epidemiology, Boston, MA, USA, 8IQVIA, Cambridge, MA, USA, 9CVS Health Clinical Trial Services, Blue Bell, PA, USA

Oral Presentations

Sunday, August 28
8:30 – 10:00 am CEST

Methods: Validation

[206] Evaluation of Mortality Data Sources Compared to the National Death Index in the HealthCore Integrated Research Database

Jamal-Allial A1, Sponholtz T1, Vojjala SK1, Papazian A1, Eshete B1, Mahmoudpour SH2, Verpillat P2, Beachler DC1

1HealthCore, Inc., Wilmington, DE, USA, 2Merck Healthcare KGaA, Darmstadt, Hessen, Germany

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Methods in Pharmacoepidemiology

(131) Changes in Incidence and Characteristics of Juvenile Idiopathic Arthritis Diagnoses from ICD-9-CM to ICD-10-CM

Parlett L1, Neikirk A1, Huang C2, Davidow A3, Haynes K4, Gerhard T2, Rose C5, Strom B2, Horton D2

1HealthCore, Inc., Wilmington, DE, USA, 2Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ, USA, 3New York University, New York, NY, USA, 4Johnson & Johnson, New Brunswick, NJ, USA, 5Thomas Jefferson University, Woodbury, NJ, USA

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Methods in Pharmacoepidemiology

(153) Data Source Heterogeneity in Multi-database Pharmacoepidemiologic Studies: an ISPE-sponsored Scoping Review

Gini R1, Pajouheshnia R2, Hall GC3, Platt RW4, Setoguchi S5, Bazelier MT2, Kaplan S6, Zhou X7, Lanes S8, Man K9, Li L10, Burcu M11, Roberto G12, Dodd C13, Duran CE2, Wientzek-Fleischmann A14, Soman K2, Lai CC15, Marinier K16, Bennett D17, Gardarsdottir H2

1Agenzia Reg Della Sanit, Firenze, Italy, 2University of Utrecht, The Hague, Zuid-Holland, Netherlands, 3Gillian Hall Epidemiology Ltd., London, Herts, UK, 4McGill University, Montreal, QC, Canada, 5Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, USA, 6Pharmaceutical Industries Ltd., Netanya, Israel, 7Pfizer Inc., New York, NY, USA, 8HealthCore, Inc., Wilmington, DE, USA, 9UCL School of Pharmacy, London, UK, 10Sanofi, Bridgewater, NJ, USA, 11Merck & Co., Inc., West Point, PA, USA, 12ARS Toscana, Firenze, Italy, 13Panalgo, Boston, MA, USA, 14Daiichi-Sankyo Europe, Germany, 15National Cheng Kung University, Tainan City, Tainan, Taiwan (Republic of China), 16IQVIA, Courbevoie, France, 17Takeda Pharmaceuticals, Lexington, MA, USA

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Pregnancy and Lactation

(228) Characteristics of Linked and Unlinked Mother-Infant in the HealthCore Integrated Research Database

Jamal-Allial A1, Guzman M1, Crowe CL1, Gallagher K1, Doherty BT1, Hoffman SR1, Avula R1, Kalloo G1, Eshete B1

1HealthCore, Inc., Wilmington, DE, USA

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Pregnancy and Lactation

(229) Impact of COVID-19 on Obstetric and Gynecologic Healthcare Utilization in a Large US Claims Database

Hoffman SR1, Crowe CL1, Guzman M1, Doherty BT1, Gallagher K1, Jamal-Allial A1, Kalloo G1

1HealthCore, Inc., Wilmington, DE, USA

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Pregnancy and Lactation

(239) Maternal and Infant Morbidity in Relation to Caesarean Section in a Large Commercially Insured Population in the US in 2019 and 2020

Doherty BT1, Lynch S1, Naavaal A2, Li C2, Cole K2, MacPhee L2, Banning L2, Sharma A2, Grabner M1, Stanek E2, Inglis T2

1HealthCore, Inc., Wilmington, DE, USA, 2Elevance Health (formerly Anthem, Inc.) Indianapolis, IN, USA

Posters
Poster Session A

Friday, August 26
8:00 am – 6:00 pm CEST

Pregnancy and Lactation

(250) Impact of COVID-19 on Pregnancy Complications & Outcomes in the HealthCore Integrated Research Database

Kalloo G1, Guzman M1, Crowe CL1, Doherty BT1, Gallagher K1, Jamal-Allial A1, Hoffman SR1

1HealthCore, Inc., Wilmington, DE, USA

Posters
Poster Session B

Saturday, August 27
8:00 am – 6:00 pm CEST

Drug Utilization Research

(120) Distribution of Samples of a New Preventive Migraine Drug and Potential Implications for Validity of Pharmacoepidemiology Studies Using Administrative Data

Hoffman SR1, Lanes S1, Crowe CL1, Daniels K1, Mawanda F2, Schroeder KM2

1HealthCore, Inc., Wilmington, DE, USA, 2Eli Lilly and Company, Indianapolis, IN, USA

Posters
Poster Session B

Saturday, August 27
8:00 am – 6:00 pm CEST

Late Breakers

(245) Spontaneous Abortions Case Definition and Gestational Age Estimation Methodological Differences

Jamal-Allial A1, Guzman M1, Daniels K1, Avula R1, Gallagher K1

1HealthCore, Inc., Wilmington, DE, USA

Posters
Spotlight Poster Session

Saturday, August 27
8:00 am – 6:00 pm CEST

Methods in Pharmacoepidemiology

(F) Time Trends in Performance of Different Mortality Data Sources Compared to the National Death Index in the HealthCore Integrated Research Database

Sponholtz T1, Jamal-Allial A1, Vojjala SK1, Papazian A1, Eshete B1, Mahmoudpour SH2, Verpillat P2, Beachler DC1

1HealthCore, Inc., Wilmington, DE, USA, 2Merck KGaA, Darmstadt, Hessen, Germany

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Methods in Pharmacoepidemiology

(152) A Step-By-Step Guide for Causal Study Design When Estimating Treatment Effects Using Real-World Data

Hoffman SR1, Gangan N1, Chen X2, Smith JL1, Tave A1, Yang Y1, dosReis S3, Grabner M1

1HealthCore, Inc., Wilmington DE, USA 2Elevance Health (formerly Anthem, Inc.), Indianapolis, IN, USA, 3University of Maryland School of Pharmacy, Baltimore, MD, USA

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Methods in Pharmacoepidemiology

(153) A Pragmatic Comparison of Logistic Regression vs. Machine Learning Methods for Propensity Score Estimation

Mai X1*, Teng CC1, Gao Y1, Governor S1, He X1, Hoffman SR1, Kalloo G1, Beachler DC1

1HealthCore, Inc., Wilmington, DE, USA
*Asterisk indicates HealthCore associate at the time of submission

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Pediatric Pharmacoepidemiology

(188) Healthcare Utilization and Treatment Among Newly Diagnosed and Prevalent Children with Juvenile Idiopathic Arthritis During the First Year of COVID-19 Pandemic in the US

Parlett L1, Yang Y1, Huang C2, Neikirk A1, Davidow A3, Haynes K4, Gerhard T2, Rose CD5, Strom BL6, Horton DB2

1HealthCore, Inc., Wilmington, DE, USA, 2Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ, USA, 3New York University School of Global Public Health, New York, NY, USA, 4Johnson & Johnson, Malvern, PA, USA, 5Thomas Jefferson University, Woodbury, NJ, USA, 6Biomedical and Health Sciences, Rutgers University, Newark, NJ, USA

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Vaccines

(257) Background Rates of Adverse Events of Special Interest for COVID-19 Vaccine Safety Monitoring Among Adults in the United States

Hobbi S1, Moll K1, Lufkin B2, Zhou CK3, Shi X2, Fingar KR1, Hu M2, Sheng M4, Joyce JC2, Burrell T4, Chillarige Y2, Beers J1, Saunders-Hastings P5, Muthuri SG1, Edwards KM6, Black S7, Kelman JA8, Reich C9, Amend KL10, Beachler DC11, Ogilvie R10, Secora A9, Seeger JD10, Lloyd P3, Thompson D3, Dimova R3, Obidi J3, Anderson SA3, Forshee RA3, Wong HL3, Shoaibi A3, Shangguan S2

1IBM Consulting, Arlington, VA, USA, 2Acumen LLC, Washington, DC, USA, 3Food and Drug Administration, Silver Spring, MD, USA, 4IBM Watson Health, Sacramento, CA, USA, 5Accenture, Ottawa, ON, Canada, 6Vanderbilt University Medical Center, Nashville, TN, USA, 7Coalition for Epidemic Preparedness Innovations (CEPI), Washington, DC, USA, 8Centers for Medicare & Medicaid Services, Baltimore, MD, USA, 9IQVIA, Cambridge, MA, USA, 10Optum, Bloomfield Hills, MI, USA, 11HealthCore, Inc., Wilmington, DE, USA

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Vaccines

(285) Capacity for Identifying Janssen Ad26.COV2.S COVID-19 Vaccination in Four US Health Insurance and State Immunization Information System Databases: Preparation for a Post Authorization Safety Study

Fuller CC1, Kawai A2, Haynes K3, Coughlin K1, Reynolds JS1, Hawrusik R1, Horgan C1, Calingaert B2, Johannes CB2, Layton JB2, Peterson A3, Praet N4, Willame C4, Yost E5, Brannan C6, McMahill-Walraven CN7, Guzman M8, Jamal-Allial A8, Nair V9, Seals RM10, Wang FT10, Selvan M9, Ma Q9, Platt R1, Gilsenan AW2, Brown J11

1Harvard Pilgrim Health Care Institute, Boston, MA, USA, 2RTI Health Solutions, Waltham, MA, USA, 3Johnson & Johnson, Malvern, PA, USA, 4Janssen, Beerse, Antwerpen Belgium, 5Janssen, Titusville, NJ, USA, 6Aetna, Hartford, CT, USA, 7CVS Health Clinical Trial Services, Blue Bell, PA, USA, 8HealthCore, Inc., Wilmington, DE, USA, 9Humana Healthcare Research, Louisville, KY, USA, 10Optum Epidemiology, Boston, MA, USA, 11TriNetX, Cambridge, MA, USA

Posters
Poster Session C

Sunday, August 28
8:00 am – 1:45 pm CEST

Vaccines

(296) Study of Myocarditis and Pericarditis Following Vaccination with COMIRNATY in Persons Under 21 Years of Age

de Luise C1, Lanes S2, Coleman J2, Cai B1, Harty B2, Miller JE2, Payne D1, Kendrick K1, Pearson G3, Truong D4, Newburger JW5

1Pfizer Inc., New York, NY, USA, 2HealthCore, Inc., Wilmington, DE, USA, 3National Heart, Lung, and Blood Institute (NHLBI)/NIH, Bethesda, MD, USA, 4University of Utah/Primary Children’s Hospital, Salt Lake City, UT, USA, 5Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA